Title
Development of a CO 2 Sensor for Extracorporeal Life Support Applications.
Abstract
Measurement of carbon dioxide (CO2) in medical applications is a well-established method for monitoring patient's pulmonary function in a noninvasive way widely used in emergency, intensive care, and during anesthesia. Even in extracorporeal-life support applications, such as Extracorporeal Carbon Dioxide Removal (ECCO2R), Extracorporeal Membrane Oxygenation (ECMO), and cardiopulmonary by-pass (CPB), measurement of the CO(2)concentration in the membrane oxygenator exhaust gas is proven to be useful to evaluate the treatment progress as well as the performance of the membrane oxygenator. In this paper, we present a new optical sensor specifically designed for the measurement of CO(2)concentration in oxygenator exhaust gas. Further, the developed sensor allows measurement of the gas flow applied to the membrane oxygenator as well as the estimation of the CO(2)removal rate. A heating module is implemented within the sensor to avoid water vapor condensation. Effects of temperature on the sensor optical elements of the sensors are disclosed, as well as a method to avoid signal-temperature dependency. The newly developed sensor has been tested and compared against a reference device routinely used in clinical practice in both laboratory and in vivo conditions. Results show that sensor accuracy fulfills the requirements of the ISO standard, and that is suitable for clinical applications.
Year
DOI
Venue
2020
10.3390/s20133613
SENSORS
Keywords
DocType
Volume
CO(2)sensor,mid-IR,extracorporeal life support devices
Journal
20
Issue
ISSN
Citations 
13.0
1424-8220
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Michele Bellancini100.34
Laura Cercenelli232.24
Stefano Severi32819.47
Guido Comai400.34
Emanuela Marcelli521.88