Title
Semi-supervised labelling of the femur in a whole-body post-mortem CT database using deep learning.
Abstract
A deep learning pipeline was developed and used to localize and classify a variety of implants in the femur contained in whole-body post-mortem computed tomography (PMCT) scans. The results provide a proof-of-principle approach for labelling content not described in medical/autopsy reports. The pipeline, which incorporated residual networks and an autoencoder, was trained and tested using n = 450 full-body PMCT scans. For the localization component, Dice scores of 0.99, 0.96, and 0.98 and mean absolute errors of 3.2, 7.1, and 4.2 mm were obtained in the axial, coronal, and sagittal views, respectively. A regression analysis found the orientation of the implant to the scanner axis and also the relative positioning of extremities to be statistically significant factors. For the classification component, test cases were properly labelled as nail (N+), hip replacement (H+), knee replacement (K+) or without-implant (I−) with an accuracy >97%. The recall for I− and H+ cases was 1.00, but fell to 0.82 and 0.65 for cases with K+ and N+. This semi-automatic approach provides a generalized structure for image-based labelling of features, without requiring time-consuming segmentation.
Year
DOI
Venue
2020
10.1016/j.compbiomed.2020.103797
Computers in Biology and Medicine
Keywords
DocType
Volume
CT,Deep learning,Autoencoder,Semi-supervised,Machine learning,Femur localization,Femoral head representation,Knee representation,Post-mortem,Forensic
Journal
122
ISSN
Citations 
PageRank 
0010-4825
1
0.39
References 
Authors
0
6
Name
Order
Citations
PageRank
C A Peña-Solórzano110.39
David Albrecht235636.66
R B Bassed310.39
J Gillam410.39
P C Harris510.39
Matthew Dimmock611.06