Title
Deep Learning Of Volumetric 3d Cnn For Fmri In Alzheimer'S Disease Classification
Abstract
Functional magnetic resonance imaging has a potential to provide insight into early detectors or biomarkers for various neurological disorders. With the advent of recent developments in deep learning, it may be possible to extract detailed information from neuroimaging data that is difficult to acquire using traditional techniques. Here we propose one such deep learning approach that makes use of a 3D Convolutional Neural Network to predict the onset of Alzheimer's disease even in a single subject based on resting state fMRI data. This approach extracts both spatial and temporal features from the 4D volume and eliminates the traditional complicated steps of feature extraction. In our experiments, a relatively simple deep learning architecture yields high performance in Alzheimer's disease classification. This illustrates the possibility of using volumetric feature extractors and classifiers as a tool to obtain biomarkers for neurological disorders and another step towards use of clinical fMRI.
Year
DOI
Venue
2020
10.1117/12.2549038
MEDICAL IMAGING 2020: BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL, AND FUNCTIONAL IMAGING
Keywords
DocType
Volume
Alzheimer's Disease, convolutional neural networks, deep learning, clinical fMRI, Neuroimaging
Conference
11317
ISSN
Citations 
PageRank 
1605-7422
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Harshit S. Parmar111.08
Brian Nutter210120.24
L. Rodney Long353456.98
Sameer K. Antani400.34
Sunanda Mitra525445.17