Title | ||
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Counting single cells and computing their heterogeneity: from phenotypic frequencies to mean value of a quantitative biomarker. |
Abstract | ||
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This tutorial presents a mathematical theory that relates the probability of sample frequencies, of Mphenotypes in an isogenic population of N cells, to the probability distribution of the sample mean of a quantitative biomarker, when the N is very large. An analogue to the statistical mechanics of canonical ensemble is discussed. |
Year | DOI | Venue |
---|---|---|
2020 | 10.1007/s40484-020-0196-3 | QUANTITATIVE BIOLOGY |
Keywords | DocType | Volume |
large deviation principle,chemical kinetics,Boltzmann's law,variational Bayesian method,maximum entropy principle | Journal | 8.0 |
Issue | ISSN | Citations |
SP2.0 | 2095-4689 | 0 |
PageRank | References | Authors |
0.34 | 0 | 2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Hong Qian | 1 | 9 | 6.22 |
Yu-Chen Cheng | 2 | 0 | 0.34 |