Title
Counting single cells and computing their heterogeneity: from phenotypic frequencies to mean value of a quantitative biomarker.
Abstract
This tutorial presents a mathematical theory that relates the probability of sample frequencies, of Mphenotypes in an isogenic population of N cells, to the probability distribution of the sample mean of a quantitative biomarker, when the N is very large. An analogue to the statistical mechanics of canonical ensemble is discussed.
Year
DOI
Venue
2020
10.1007/s40484-020-0196-3
QUANTITATIVE BIOLOGY
Keywords
DocType
Volume
large deviation principle,chemical kinetics,Boltzmann's law,variational Bayesian method,maximum entropy principle
Journal
8.0
Issue
ISSN
Citations 
SP2.0
2095-4689
0
PageRank 
References 
Authors
0.34
0
2
Name
Order
Citations
PageRank
Hong Qian196.22
Yu-Chen Cheng200.34