Title
Automated Segmentation of the Clinical Target Volume in the Planning CT for Breast Cancer Using Deep Neural Networks
Abstract
3-D radiotherapy is an effective treatment modality for breast cancer. In 3-D radiotherapy, delineation of the clinical target volume (CTV) is an essential step in the establishment of treatment plans. However, manual delineation is subjective and time consuming. In this study, we propose an automated segmentation model based on deep neural networks for the breast cancer CTV in planning computed tomography (CT). Our model is composed of three stages that work in a cascade manner, making it applicable to real-world scenarios. The first stage determines which slices contain CTVs, as not all CT slices include breast lesions. The second stage detects the region of the human body in an entire CT slice, eliminating boundary areas, which may have side effects for the segmentation of the CTV. The third stage delineates the CTV. To permit the network to focus on the breast mass in the slice, a novel dynamically strided convolution operation, which shows better performance than standard convolution, is proposed. To train and evaluate the model, a large dataset containing 455 cases and 50 425 CT slices is constructed. The proposed model achieves an average dice similarity coefficient (DSC) of 0.802 and 0.801 for right-0 and left-sided breast, respectively. Our method shows superior performance to that of previous state-of-the-art approaches.
Year
DOI
Venue
2022
10.1109/TCYB.2020.3012186
IEEE Transactions on Cybernetics
Keywords
DocType
Volume
Breast Neoplasms,Female,Humans,Image Processing, Computer-Assisted,Neural Networks, Computer,Radiotherapy Planning, Computer-Assisted,Tomography, X-Ray Computed
Journal
52
Issue
ISSN
Citations 
5
2168-2267
0
PageRank 
References 
Authors
0.34
16
5
Name
Order
Citations
PageRank
Xiaofeng Qi1242.89
Junjie Hu211220.50
Lei Zhang327122.04
Sen Bai400.68
Zhang Yi551234.06