Name
Abstract | ||
|---|---|---|
BackgroundRNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can increase both the transcriptome and proteome diversity. The automatic detection of RNA-editing from RNA-seq data is computational intensive and limited to small data sets, thus preventing a reliable genome-wide characterisation of such process.ResultsIn this work we introduce HPC-REDItools, an upgraded tool for accurate RNA-editing events discovery from large dataset repositories. Availability: https://github.com/BioinfoUNIBA/REDItools2.ConclusionsHPC-REDItools is dramatically faster than the previous version, REDItools, enabling big-data analysis by means of a MPI-based implementation and scaling almost linearly with the number of available cores. |
Year | DOI | Venue |
|---|---|---|
2020 | 10.1186/s12859-020-03562-x | BMC BIOINFORMATICS |
Keywords | DocType | Volume |
RNA-editing,High Performance Computing,REDItools,Next Generation Sequencing,Sequence Analysis,Bioinformatics pipeline | Journal | 21 |
Issue | ISSN | Citations |
SUPnan | 1471-2105 | 0 |
PageRank | References | Authors |
0.34 | 0 | 9 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Tiziano Flati | 1 | 0 | 1.35 |
| Silvia Gioiosa | 2 | 0 | 1.01 |
| Nicola Spallanzani | 3 | 0 | 0.34 |
| Ilario Tagliaferri | 4 | 0 | 0.34 |
| Maria Angela Diroma | 5 | 9 | 2.40 |
| Graziano Pesole | 6 | 3 | 2.19 |
| Giovanni Chillemi | 7 | 1 | 2.42 |
| Ernesto Picardi | 8 | 152 | 15.76 |
| Tiziana Castrignanò | 9 | 103 | 10.37 |