Abstract | ||
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Targeted interrogation of brain networks through invasive brain stimulation has become an increasingly important research tool as well as therapeutic modality. The majority of work with this emerging capability has been focused on open-loop approaches. Closed-loop techniques, however, could improve neuromodulatory therapies and research investigations by optimizing stimulation approaches using neurally informed, personalized targets. Implementing closed-loop systems is challenging particularly with regard to applying consistent strategies considering inter-individual variability. In particular, during intracranial epilepsy monitoring, where much of this research is currently progressing, electrodes are implanted exclusively for clinical reasons. Thus, detection and stimulation sites must be participant- and task-specific. The system must run in parallel with clinical systems, integrate seamlessly with existing setups, and ensure safety features are in place. In other words, a robust, yet flexible platform is required to perform different tests with a single participant and to comply with clinical requirements. |
Year | DOI | Venue |
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2020 | 10.1016/j.neuroimage.2020.117314 | NeuroImage |
Keywords | DocType | Volume |
Closed-loop,Direct electrical stimulation,Neuromodulation,intracranial EEG | Journal | 223 |
ISSN | Citations | PageRank |
1053-8119 | 1 | 0.34 |
References | Authors | |
0 | 14 |
Name | Order | Citations | PageRank |
---|---|---|---|
Rina Zelmann | 1 | 1 | 0.34 |
Angelique C Paulk | 2 | 1 | 1.36 |
Ishita Basu | 3 | 15 | 3.60 |
Anish Sarma | 4 | 1 | 0.34 |
Ali Yousefi | 5 | 12 | 5.63 |
Britni Crocker | 6 | 1 | 0.34 |
Emad Eskandar | 7 | 1 | 0.34 |
Ziv Williams | 8 | 3 | 1.40 |
G. Rees Cosgrove | 9 | 4 | 1.10 |
Daniel S Weisholtz | 10 | 1 | 0.34 |
Darin D. Dougherty | 11 | 6 | 2.60 |
Wilson Truccolo | 12 | 64 | 12.78 |
Alik S. Widge | 13 | 4 | 2.20 |
Sydney S. Cash | 14 | 20 | 10.14 |