Title
Deep Recurrent Neural Networks for Automatic Detection of Sleep Apnea from Single Channel Respiration Signals.
Abstract
Sleep apnea is a common sleep disorder that causes repeated breathing interruption during sleep. The performance of automated apnea detection methods based on respiratory signals depend on the signals considered and feature extraction methods. Moreover, feature engineering techniques are highly dependent on the experts' experience and their prior knowledge about different physiological signals and conditions of the subjects. To overcome these problems, a novel deep recurrent neural network (RNN) framework is developed for automated feature extraction and detection of apnea events from single respiratory channel inputs. Long short-term memory (LSTM) and bidirectional long short-term memory (BiLSTM) are investigated to develop the proposed deep RNN model. The proposed framework is evaluated over three respiration signals: Oronasal thermal airflow (FlowTh), nasal pressure (NPRE), and abdominal respiratory inductance plethysmography (ABD). To demonstrate our results, we use polysomnography (PSG) data of 17 patients with obstructive, central, and mixed apnea events. Our results indicate the effectiveness of the proposed framework in automatic extraction for temporal features and automated detection of apneic events over the different respiratory signals considered in this study. Using a deep BiLSTM-based detection model, the NPRE signal achieved the highest overall detection results with true positive rate (sensitivity) = 90.3%, true negative rate (specificity) = 83.7%, and area under receiver operator characteristic curve = 92.4%. The present results contribute a new deep learning approach for automated detection of sleep apnea events from single channel respiration signals that can potentially serve as a helpful and alternative tool for the traditional PSG method.
Year
DOI
Venue
2020
10.3390/s20185037
SENSORS
Keywords
DocType
Volume
sleep apnea,deep learning,recurrent neural network,long short-term memory,sleep-disordered breathing
Journal
20
Issue
ISSN
Citations 
18
1424-8220
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Hisham ElMoaqet1101.59
Mohammad Eid200.34
Martin Glos3174.76
Mutaz Ryalat4123.51
Thomas Penzel54815.35