Title
Identification of Melanoma From Hyperspectral Pathology Image Using 3D Convolutional Networks
Abstract
Skin biopsy histopathological analysis is one of the primary methods used for pathologists to assess the presence and deterioration of melanoma in clinical. A comprehensive and reliable pathological analysis is the result of correctly segmented melanoma and its interaction with benign tissues, and therefore providing accurate therapy. In this study, we applied the deep convolution network on the hyperspectral pathology images to perform the segmentation of melanoma. To make the best use of spectral properties of three dimensional hyperspectral data, we proposed a 3D fully convolutional network named Hyper-net to segment melanoma from hyperspectral pathology images. In order to enhance the sensitivity of the model, we made a specific modification to the loss function with caution of false negative in diagnosis. The performance of Hyper-net surpassed the 2D model with the accuracy over 92%. The false negative rate decreased by nearly 66% using Hyper-net with the modified loss function. These findings demonstrated the ability of the Hyper-net for assisting pathologists in diagnosis of melanoma based on hyperspectral pathology images.
Year
DOI
Venue
2021
10.1109/TMI.2020.3024923
IEEE Transactions on Medical Imaging
Keywords
DocType
Volume
Biopsy,Humans,Melanoma,Skin,Skin Neoplasms
Journal
40
Issue
ISSN
Citations 
1
0278-0062
0
PageRank 
References 
Authors
0.34
0
8
Name
Order
Citations
PageRank
Qian Wang100.34
Li Sun277.20
Yan Wang353.49
Mei Zhou4105.28
Menghan Hu520.70
Jiangang Chen600.34
ying wen71307.60
Qingli Li886.68