Title
Parameter Estimation Of Hemodynamic Cardiovascular Model For Synthesis Of Photoplethysmogram Signal
Abstract
Synthesis of accurate, personalize photoplethysmogram (PPG) signal is important to interpret, analyze and predict cardiovascular disease progression. Generative models like Generative Adversarial Networks (GANs) can be used for signal synthesis, however, they are difficult to map to the underlying pathophysiological conditions. Hence, we propose a PPG synthesis strategy that has been designed using a cardiovascular system, modeled through the hemodynamic principle. The modeled architecture is composed of a two-chambered heart along with the systemic-pulmonic blood circulation and a baroreflex auto-regulation mechanism to control the arterial blood pressure. The comprehensive PPG signal is synthesized from the cardiac pressure-flow dynamics. In order to tune the modeled cardiac parameters with respect to a measured PPG data, a novel feature extraction strategy has been employed along with the particle swarm optimization heuristics. Our results demonstrate that the synthesized PPG is accurately followed the morphological changes of the ground truth (GT) signal with an RMSE of 0:003 occurring due to the Coronary Artery Disease (CAD) which is caused by an obstruction in the artery.
Year
DOI
Venue
2020
10.1109/EMBC44109.2020.9175352
42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20
DocType
Volume
ISSN
Conference
2020
1557-170X
Citations 
PageRank 
References 
0
0.34
0
Authors
6
Name
Order
Citations
PageRank
Dibyendu Roy126.72
Oishee Mazumder2147.05
Kingshuk Chakravarty3418.93
Aniruddha Sinha414533.50
Avik Ghose59323.94
Arpan Pal619551.41