Name
Title | ||
|---|---|---|
Deep Convolutional Neural Network And Reverse Biorthogonal Wavelet Scalograms For Automatic Identification Of High Frequency Micro-Scale Spike Transients In The Post-Hypoxic-Ischemic Eeg |
Abstract | ||
|---|---|---|
Diagnosis of hypoxic-ischemic encephalopathy (HIE) is currently limited and prognostic biological markers are required for early identification of at risk infants at birth. Using pre-clinical data from our fetal sheep models, we have shown that micro-scale EEG patterns, such as high-frequency spikes and sharp waves, evolve superimposed on a significantly suppressed background during the early hours of recovery (0-6 h), after an HI insult. In particular, we have demonstrated that the number of micro-scale gamma spike transients peaks within the first 2-2.5 hours of the insult and automatically quantified sharp waves in this period are predictive of neural outcome. This period of time is optimal for the initiation of neuroprotection treatments such as therapeutic hypothermia, which has a limited window of opportunity for implementation of 6 h or less after an HI insult. Clinically, it is hard to determine when an insult has started and thus the window of opportunity for treatment. Thus, reliable automatic algorithms that could accurately identify EEG patterns that denote the phase of injury is a valuable clinical tool. We have previously developed successful machine-learning strategies for the identification of HI micro- scale EEG patterns in a preterm fetal sheep model of HI. This paper employs, for the first time, reverse biorthogonal Wavelet-Scalograms (WS) as the inputs to a 17-layer deep-trained convolutional neural network (CNN) for the precise identification of high-frequency micro-scale spike transients that occur in the 80-120Hz gamma band during first 2 h period of an HI insult. The rbio-WS-CNN classifier robustly identified spike transients with an exceptionally high-performance of 99.82%. |
Year | DOI | Venue |
|---|---|---|
2020 | 10.1109/EMBC44109.2020.9176499 | 42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20 |
DocType | Volume | ISSN |
Conference | 2020 | 1557-170X |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Hamid Abbasi | 1 | 4 | 3.42 |
| Alistair J. Gunn | 2 | 3 | 3.07 |
| Laura Bennet | 3 | 19 | 5.58 |
| Charles P Unsworth | 4 | 14 | 7.47 |