Title
Learning Latent Spiculated Features For Lung Nodule Characterization
Abstract
Computer-aided Diagnosis (CAD) systems have long aimed to be used in clinical practice to help doctors make decisions by providing a second opinion. However, most machine learning based CAD systems make predictions without explicitly showing how their predictions were generated. Since the cognitive process of the diagnostic imaging interpretation involves various visual characteristics of the region of interest, the explainability of the results should leverage those characteristics. We encode visual characteristics of the region of interest based on pairs of similar images rather than the image content by itself. Using a Siamese convolutional neural network (SCNN), we first learn the similarity among nodules, then encode image content using the SCNN similarity-based feature representation, and lastly, we apply the K-nearest neighbor (KNN) approach to make diagnostic characterizations using the Siamese-based image features. We demonstrate the feasibility of our approach on spiculation, a visual characteristic that radiologists consider when interpreting the degree of cancer malignancy, and the NIH/NCI Lung Image Database Consortium (LIDC) dataset that contains both spiculation and malignancy characteristics for lung nodules.
Year
DOI
Venue
2020
10.1109/EMBC44109.2020.9175720
42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20
DocType
Volume
ISSN
Conference
2020
1557-170X
Citations 
PageRank 
References 
0
0.34
0
Authors
5
Name
Order
Citations
PageRank
Bowen Qiu100.34
Jacob D. Furst254556.63
Alexander Rasin32950209.48
Roselyne Tchoua400.34
Daniela Stan Raicu546946.22