Name
Title | ||
|---|---|---|
A Method For Deciphering Major Drivers Of Bacterial Iron Stress Response In The Presence Of Oxidative Stressors |
Abstract | ||
|---|---|---|
This paper describes a method for deciphering major drivers of bacterial stress response using an empirically informed computational approach. We develop a working model of iron flux regulation and concomitant oxidative stress response in Escherichia coli. The integrated model is used to investigate the temporal effects of iron and hydrogen peroxide stress on bacterial growth and metabolism. We employ a sensitivity analysis platform and, using various measures, probe for major mechanistic drivers of the bacterial response to iron stress. |
Year | DOI | Venue |
|---|---|---|
2020 | 10.1109/EMBC44109.2020.9176518 | 42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20 |
DocType | Volume | ISSN |
Conference | 2020 | 1557-170X |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Daniel C Ajuzie | 1 | 0 | 0.34 |
| Seyed A Arshad | 2 | 0 | 0.34 |
| Komal S Rasaputra | 3 | 0 | 0.34 |
| Elebeoba E May | 4 | 0 | 1.69 |