Title | ||
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Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients |
Abstract | ||
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Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG. |
Year | DOI | Venue |
---|---|---|
2020 | 10.1109/EMBC44109.2020.9176326 | 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) |
Keywords | DocType | Volume |
Electroencephalography,Epilepsy,Heart Rate,Humans,Retrospective Studies,Vagus Nerve Stimulation | Conference | 2020 |
ISSN | ISBN | Citations |
2375-7477 | 978-1-7281-1991-5 | 0 |
PageRank | References | Authors |
0.34 | 0 | 7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Plesinger, F. | 1 | 3 | 8.70 |
Halamek, J. | 2 | 3 | 9.72 |
Jan Chládek | 3 | 0 | 1.01 |
Pavel Jurák | 4 | 5 | 12.45 |
I Dolezalova | 5 | 0 | 0.34 |
J Chrastina | 6 | 0 | 0.34 |
Milan Brázdil | 7 | 23 | 4.78 |