Paper Info
Title
Transmural Temperature Monitoring To Quantify Thermal Conduction And Lesion Formation During Gastric Ablation, An Emerging Therapy For Gastric Dysrhythmias
Abstract
Gastric ablation is emerging as a potential therapy for electrical dysrhythmias associated with gastric disorders. Thermal conduction properties of gastric tissue during ablation have not yet been defined, but are necessary for optimizing the technique and translating ablation to clinical therapy. We developed custom needle-based transmural temperature probes to quantify the temperature of gastric tissue during ablation. These probes were applied in vivo in pigs (n=5), during gastric ablation (70 degrees C, 10 s duration), at distances of 2.5 - 20 mm from the ablation catheter tip. Thermal response of the tissue was non-linear; the maximum temperature increase from baseline (33.3 +/- 1.0 degrees C) was observed at the closest temperature probe to the catheter tip (2.5 mm, 14.9 degrees C), and temperature change decreased with distance from the catheter tip. Probes positioned between 5 20 mm from the catheter tip recorded temperature increases of less than 5.6 degrees C. This study provides methods for monitoring temperature during in vivo ablation, and demonstrates that functional temperature increases from ablation were restricted to within approximately 5 mm of the catheter. These methods can now be applied to optimize effective ablation parameters, and to inform models of gastric ablation.
Year
DOI
Venue
2020
10.1109/EMBC44109.2020.9176026
42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20
DocType
Volume
ISSN
Conference
2020
1557-170X
Citations 
PageRank 
References 
0
0.34
0
Authors
8
Name
Order
Citations
PageRank
Mikhael Sayat100.34
Zahra Aghababaie202.37
Leo K Cheng37037.48
Niranchan Paskaranandavadivel469.30
Recep Avci546.54
Johan Rickus600.34
Wharengaro Ruha700.34
Timothy R. Angeli836.46