Title
Roughness-Length-Based Characteristic Analysis Of Intracranial Eeg And Epileptic Seizure Prediction
Abstract
To identify precursors of epileptic seizures, an EEG characteristic analysis is carried out based on a roughness-length method, where fractal dimensions and intercept values are extracted to measure the structure complexity and the amplitude roughness of EEG signals in different phases. Using the significant changes of the fractal dimension and intercept in the preictal phase with respect to those in the interictal phase, a patient-specific seizure prediction algorithm is then proposed by combining with a gradient boosting classifier. The probabilistic outputs of the trained gradient boosting classifier are further processed by threshold comparison and rule-based judgment to distinguish preictal EEG from interictal EEG and to generate seizure alerts. The prediction algorithm was evaluated on 20 patients' intracranial EEG recordings from the Freiburg EEG database, which contains the preictal periods of 65 seizures and 499h interictal EEG. Setting the seizure prediction horizon as 2min, averaged sensitivity values of 90.42% and 91.67% with averaged false prediction rates of 0.12/h and 0.10/h were achieved for seizure occurrence periods of 30 and 50min, respectively. These results demonstrate the ability of fractal dimension and intercept metrics in predicting the occurrence of seizures.
Year
DOI
Venue
2020
10.1142/S0129065720500720
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
Keywords
DocType
Volume
Seizure prediction, intracranial EEG, roughness-length method, fractal dimension, intercept, gradient boosting classifier
Journal
30
Issue
ISSN
Citations 
12
0129-0657
1
PageRank 
References 
Authors
0.34
0
3
Name
Order
Citations
PageRank
Yanli Zhang1473.68
Rendi Yang210.34
Weidong Zhou3173.21