Title
Massively Parallel Causal Inference of Whole Brain Dynamics at Single Neuron Resolution
Abstract
Empirical Dynamic Modeling (EDM) is a nonlinear time series causal inference framework. The latest implementation of EDM, cppEDM, has only been used for small datasets due to computational cost. With the growth of data collection capabilities, there is a great need to identify causal relationships in large datasets. We present mpEDM, a parallel distributed implementation of EDM optimized for modern GPU-centric supercomputers. We improve the original algorithm to reduce redundant computation and optimize the implementation to fully utilize hardware resources such as GPUs and SIMD units. As a use case, we run mpEDM on AI Bridging Cloud Infrastructure (ABCI) using datasets of an entire animal brain sampled at single neuron resolution to identify dynamical causation patterns across the brain. mpEDM is 1,530× faster than cppEDM and a dataset containing 101,729 neuron was analyzed in 199 seconds on 512 nodes. This is the largest EDM causal inference achieved to date.
Year
DOI
Venue
2020
10.1109/ICPADS51040.2020.00035
2020 IEEE 26th International Conference on Parallel and Distributed Systems (ICPADS)
Keywords
DocType
ISSN
Empirical Dynamic Modeling,Causal Inference,Parallel Distributed Computing,GPU,High-Performance Computing,Neuroscience
Conference
1521-9097
ISBN
Citations 
PageRank 
978-1-7281-8382-4
0
0.34
References 
Authors
0
8