Title
Multimodal Spatio-Temporal Deep Learning Approach For Neonatal Postoperative Pain Assessment
Abstract
The current practice for assessing neonatal postoperative pain relies on bedside caregivers. This practice is subjective, inconsistent, slow, and discontinuous. To develop a reliable medical interpretation, several automated approaches have been proposed to enhance the current practice. These approaches are unimodal and focus mainly on assessing neonatal procedural (acute) pain. As pain is a multimodal emotion that is often expressed through multiple modalities, the multimodal assessment of pain is necessary especially in case of postoperative (acute prolonged) pain. Additionally, spatio-temporal analysis is more stable over time and has been proven to be highly effective at minimizing misclassification errors. In this paper, we present a novel multimodal spatiotemporal approach that integrates visual and vocal signals and uses them for assessing neonatal postoperative pain. We conduct comprehensive experiments to investigate the effectiveness of the proposed approach. We compare the performance of the multimodal and unimodal postoperative pain assessment, and measure the impact of temporal information integration. The experimental results, on a real-world dataset, show that the proposed multimodal spatio-temporal approach achieves the highest AUC (0.87) and accuracy (79%), which are on average 6.67% and 6.33% higher than unimodal approaches. The results also show that the integration of temporal information markedly improves the performance as compared to the non-temporal approach as it captures changes in the pain dynamic. These results demonstrate that the proposed approach can be used as a viable alternative to manual assessment, which would tread a path toward fully automated pain monitoring in clinical settings, point-of-care testing, and homes.
Year
DOI
Venue
2021
10.1016/j.compbiomed.2020.104150
COMPUTERS IN BIOLOGY AND MEDICINE
Keywords
DocType
Volume
Postoperative pain, Acute prolonged pain, Neonatal pain classification, Infant monitoring, Neonatal Intensive Care Unit (NICU), Multimodal, Facial expression, Body movement, Crying sound
Journal
129
ISSN
Citations 
PageRank 
0010-4825
1
0.35
References 
Authors
12
6
Name
Order
Citations
PageRank
Md Sirajus Salekin110.35
Ghada Zamzmi252.89
Dmitry B. Goldgof32021198.90
Ranga Kasturi41487168.00
Thao Ho510.69
Yu Sun620835.82