Title
Mathematical model of brain tumour growth with drug resistance
Abstract
Brain tumours are masses of abnormal cells that can grow in an uncontrolled way in the brain. There are different types of malignant brain tumours. Gliomas are malignant brain tumours that grow from glial cells and are identified as astrocytoma, oligodendroglioma, and ependymoma. We study a mathematical model that describes glia-neuron interaction, glioma, and chemotherapeutic agent. In this work, we consider drug sensitive and resistant glioma cells. We show how continuous and pulsed chemotherapy can kill glioma cells with a minimal loss of neurons. (c) 2021 Elsevier B.V. All rights reserved.
Year
DOI
Venue
2021
10.1016/j.cnsns.2021.106013
COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION
Keywords
DocType
Volume
Brain, Tumour, Chemotherapy, Drug resistance, Glia-neuron interaction
Journal
103
ISSN
Citations 
PageRank 
1007-5704
0
0.34
References 
Authors
0
12