Title
Synthesizing Multi-Contrast Mr Images Via Novel 3d Conditional Variational Auto-Encoding Gan
Abstract
As two different modalities of medical images, Magnetic Resonance (MR) and Computer Tomography (CT), provide mutually-complementary information to doctors in clinical applications. However, to obtain both images sometimes is cost-consuming and unavailable, particularly for special populations. For example, patients with metal implants are not suitable for MR scanning. Also, it is probably infeasible to acquire multi-contrast MR images during once clinical scanning. In this context, to synthesize needed MR images for patients whose CT images are available becomes valuable. To this end, we present a novel generative network, called CAE-ACGAN, which incorporates the advantages of Variational Auto-Encoder (VAE) and Generative Adversarial Network (GAN) with an auxiliary discriminative classifier network. We apply this network to synthesize multi-contrast MR images from single CT and conduct experiments on brain datasets. Our main contributions can be summarized as follows: 1)We alleviate the problems of images blurriness and mode collapse by integrating the advantages of VAE and GAN; 2) We solve the complicated cross-domain, multi-contrast MR synthesis task using the proposed network; 3) The technique of random-extraction-patches is used to lower the limit of insufficient training data, enabling to obtain promising results even with limited available data; 4) By comparing with other typical networks, we are able to yield nearer-real, higher-quality synthetic MR images, demonstrating the effectiveness and stability of our proposed network.
Year
DOI
Venue
2021
10.1007/s11036-020-01678-1
MOBILE NETWORKS & APPLICATIONS
Keywords
DocType
Volume
MR synthesis, 3D, Multi-contrast, Auto-encoding, Generative adversarial network
Journal
26
Issue
ISSN
Citations 
1
1383-469X
1
PageRank 
References 
Authors
0.34
23
7
Name
Order
Citations
PageRank
Huan Yang141.06
Xianling Lu210.34
Shuihua Wang3156487.49
Zhihai Lu4151.25
Jian Yao510.34
Yizhang Jiang638227.24
pengjiang qian7305.48