Title | ||
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Multi-objective optimization of a nonlinear switched time-delay system in microbial fed-batch process |
Abstract | ||
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•Considering uncoupled, free terminal time, dha regulator, intracellular and extracellular environment, a nonlinear switched time-delay system model is established involving four time-delays and four switching modes for fed-batch fermentation of glycerol to 1,3-PD.•For determining optimal time-delays, a robustness index is given based expectation and variance.•The gradient formulas of the indices and constraints with respect to time-delays, terminal time and feeding rates are given with their proofs.•Considering the three-objective optimization model, we formulate an algorithm and obtain the valuable Pareto solutions by large scale calculation. |
Year | DOI | Venue |
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2020 | 10.1016/j.jfranklin.2020.07.036 | Journal of the Franklin Institute |
DocType | Volume | Issue |
Journal | 357 | 17 |
ISSN | Citations | PageRank |
0016-0032 | 0 | 0.34 |
References | Authors | |
0 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Xiaohua Gao | 1 | 0 | 0.34 |
Jingang Zhai | 2 | 6 | 2.12 |
Enmin Feng | 3 | 111 | 24.41 |