Title
Toric geometry of the Cavender-Farris-Neyman model with a molecular clock
Abstract
We give a combinatorial description of the toric ideal of invariants of the Cavender-Farris-Neyman model with a molecular clock (CFN-MC) on a rooted binary phylogenetic tree and prove results about the polytope associated to this toric ideal. Key results about the polyhedral structure include that the number of vertices of this polytope is a Fibonacci number, the facets of the polytope can be described using the combinatorial “cluster” structure of the underlying rooted tree, and the volume is equal to an Euler zig-zag number. The toric ideal of invariants of the CFN-MC model has a quadratic Gröbner basis with squarefree initial terms. Finally, we show that the Ehrhart polynomial of these polytopes, and therefore the Hilbert series of the ideals, depends only on the number of leaves of the underlying binary tree, and not on the topology of the tree itself. These results are analogous to classic results for the Cavender-Farris-Neyman model without a molecular clock. However, new techniques are required because the molecular clock assumption destroys the toric fiber product structure that governs group-based models without the molecular clock.
Year
DOI
Venue
2021
10.1016/j.aam.2020.102119
Advances in Applied Mathematics
Keywords
DocType
Volume
92D15,14M25,62R01
Journal
123
ISSN
Citations 
PageRank 
0196-8858
0
0.34
References 
Authors
0
2
Name
Order
Citations
PageRank
Jane Ivy Coons100.34
Seth Sullivant29319.17