Paper Info
Title
An In Vitro Circulatory Device For Studying Blood Flow Electrical Impedance In Human Common Carotid Arteries
Abstract
To study the blood flow electrical impedance in human common carotid arteries in vitro, a circulatory device simulating the arterial pulsatile blood flow is designed and fabricated. Using the detected physiological blood pressure and flow rate waveforms, a five-element lumped parameter model is established, in which the real blood pressure waveform at the common carotid artery and the input impedance of downstream cerebrovascular bed are set as simulated targets. Based on the model, the parameter values of each component are determined using the trial and error method. Furthermore, the feasibility analysis is performed with the software Simulink. Finally, corresponding to the values of each component, appropriate elements are selected to construct the circulatory device in vitro for simulating the blood pulsatile blood flow at the common carotid artery. The results indicate that the circulatory device can generate stable pressure and impedance waveforms similar to the physiological cases. The circulatory device provides an ideal experimental platform for further studying the blood flow electrical impedance in human common carotid artery in vitro.
Year
DOI
Venue
2020
10.1109/ICCA51439.2020.9264317
2020 IEEE 16TH INTERNATIONAL CONFERENCE ON CONTROL & AUTOMATION (ICCA)
DocType
ISSN
Citations 
Conference
1948-3449
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Hai-Jun Zhang100.34
Hua Shen200.34
Yong-Jiang Li300.34
Kai-Rong Qin404.06