Title | ||
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Quick Evaluation Of Lower Leg Ischemia In Patients With Peripheral Arterial Disease By Time Maximum Intensity Projection Ct Angiography: A Pilot Study |
Abstract | ||
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Background The purpose of this study is to evaluate a new method involving time maximum intensity projection (t-MIP) postprocessed from dynamic computed tomographic angiography (dyn-CTA) in diagnosing peripheral arterial disease (PAD). Methods A population of 34 patients with known PAD was examined with a combined CTA protocol consisting of a standard CTA (s-CTA) scan of the lower extremities and a dyn-CTA scan of the calves. For each lower leg, t-MIP images consisting of the MIP0 (sagittal MIP), MIP+theta (45 degrees lateral MIP), and MIP-theta (- 45 degrees lateral MIP) were automatically generated from dyn-CTA. An objective evaluation of the vascular CT attenuation of the best enhancement phase of dyn-CTA and t-MIP was measured; a subjective evaluation of vessel stenosis and occlusion was performed, assigning a score for t-MIP and s-CTA. The CT attenuation of t-MIP and dyn-CTA was compared, as were the runoff scores of t-MIP and s-CTA. Results The CT attenuation of t-MIP CTA of three vascular segments from 68 lower extremities was higher than that of the best enhancement phase of dyn-CTA and s-CTA, with statistically significant differences at the posterior tibial artery and fibular artery (all p < 0.05). There were strong correlations (r >= 0.75, p < 0.05) of the runoff scores between t-MIP and s-CTA. Conclusions There is potential clinical applicability of t-MIP in assisting with the diagnosis of lower leg vascular stenosis in dyn-CTA with reliable diagnostic accuracy and convenient immediacy. |
Year | DOI | Venue |
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2021 | 10.1186/s12880-020-00537-5 | BMC MEDICAL IMAGING |
Keywords | DocType | Volume |
Peripheral arterial disease, Computed tomographic angiography, Maximum intensity projection | Journal | 21 |
Issue | ISSN | Citations |
1 | 1471-2342 | 0 |
PageRank | References | Authors |
0.34 | 0 | 9 |
Name | Order | Citations | PageRank |
---|---|---|---|
Daming Zhang | 1 | 0 | 0.34 |
Xueyan Zhou | 2 | 0 | 0.68 |
Haiping Zhang | 3 | 0 | 0.34 |
Xiaobing Fan | 4 | 0 | 1.69 |
Zehong Lin | 5 | 0 | 0.34 |
Huadan Xue | 6 | 1 | 1.37 |
Yining Wang | 7 | 0 | 0.34 |
Zhengyu Jin | 8 | 0 | 0.34 |
Yuexin Chen | 9 | 0 | 0.34 |