Title
Quick Evaluation Of Lower Leg Ischemia In Patients With Peripheral Arterial Disease By Time Maximum Intensity Projection Ct Angiography: A Pilot Study
Abstract
Background The purpose of this study is to evaluate a new method involving time maximum intensity projection (t-MIP) postprocessed from dynamic computed tomographic angiography (dyn-CTA) in diagnosing peripheral arterial disease (PAD). Methods A population of 34 patients with known PAD was examined with a combined CTA protocol consisting of a standard CTA (s-CTA) scan of the lower extremities and a dyn-CTA scan of the calves. For each lower leg, t-MIP images consisting of the MIP0 (sagittal MIP), MIP+theta (45 degrees lateral MIP), and MIP-theta (- 45 degrees lateral MIP) were automatically generated from dyn-CTA. An objective evaluation of the vascular CT attenuation of the best enhancement phase of dyn-CTA and t-MIP was measured; a subjective evaluation of vessel stenosis and occlusion was performed, assigning a score for t-MIP and s-CTA. The CT attenuation of t-MIP and dyn-CTA was compared, as were the runoff scores of t-MIP and s-CTA. Results The CT attenuation of t-MIP CTA of three vascular segments from 68 lower extremities was higher than that of the best enhancement phase of dyn-CTA and s-CTA, with statistically significant differences at the posterior tibial artery and fibular artery (all p < 0.05). There were strong correlations (r >= 0.75, p < 0.05) of the runoff scores between t-MIP and s-CTA. Conclusions There is potential clinical applicability of t-MIP in assisting with the diagnosis of lower leg vascular stenosis in dyn-CTA with reliable diagnostic accuracy and convenient immediacy.
Year
DOI
Venue
2021
10.1186/s12880-020-00537-5
BMC MEDICAL IMAGING
Keywords
DocType
Volume
Peripheral arterial disease, Computed tomographic angiography, Maximum intensity projection
Journal
21
Issue
ISSN
Citations 
1
1471-2342
0
PageRank 
References 
Authors
0.34
0
9
Name
Order
Citations
PageRank
Daming Zhang100.34
Xueyan Zhou200.68
Haiping Zhang300.34
Xiaobing Fan401.69
Zehong Lin500.34
Huadan Xue611.37
Yining Wang700.34
Zhengyu Jin800.34
Yuexin Chen900.34