Title
Smoothed Particle Hydrodynamics Simulation Of Biphasic Soft Tissue And Its Medical Applications
Abstract
Modeling the coupled fluid and elastic mechanics of blood perfused soft tissues is important for medical applications. In particular, the current study aims to capture the effect of tissue swelling and the transport of blood through damaged tissue under bleeding or hemorrhaging conditions. The soft tissue is considered a dynamic poro-hyperelastic material with blood-filled voids. A biphasic formulation-effectively, a generalization of Darcy's law-is utilized, treating the phases as occupying fractions of the same volume. A Stokes-like friction force and a pressure that penalizes deviations from volume fractions summing to unity serve as the interaction force between solid and liquid phases. The resulting equations for both phases are discretized with the method of smoothed particle hydrodynamics (SPH). The solver is validated separately on each phase and demonstrates good agreement with exact solutions in test problems. Simulations of oozing, hysteresis, swelling, drying and shrinkage, and tissue fracturing and hemorrhage are shown in the paper.
Year
DOI
Venue
2021
10.1007/s11517-020-02283-w
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
Keywords
DocType
Volume
Soft tissue, Smoothed particle hydrodynamics, Theory of porous media, Hyperelasticity, Multiphases
Journal
59
Issue
ISSN
Citations 
1
0140-0118
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Yi-Jui Chang100.34
Peyman Benharash201.69
Erik Dutson3246.21
Jeff D. Eldredge4304.99