Paper Info
Title
Biological Processes underlying the Reinforcing Primary Qi Delivered by Ginseng.
Abstract
Ginseng is an important herbal medicine in traditional Chinese medicine (TCM) with therapeutic properties of “reinforcing primary qi” and “pulse restoring and blocking depletion” that are mentioned in both TCM textbooks and the Pharmacopoeia of the People’s Republic of China. However, the underlying mechanisms are still under exploration. In this study, based on evidenced bioactive compounds and targeted genes/proteins, top-level functional annotation towards gene ontology biological processes was deployed and then validated with transcript microarray data. As a result, a kernel candidate regulation network was constructed towards the therapeutic properties of ginseng identified in TCM. Functional annotation indicated three associated biological processes e.g. (1) cell killing, (2) rhythmic process, and (3) growth. In short, through regulating the three processes, the therapeutic properties of “reinforcing primary qi” and “pulse restoring and blocking depletion” identified in TCM can be roughly elaborated and validated.
Year
DOI
Venue
2020
10.1109/BIBM49941.2020.9313531
BIBM
DocType
Citations 
PageRank 
Conference
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Guang Zheng102.70
Junnan Chen201.69
Yajie Gao301.01
Hongtao Guo4299.71