Name
Abstract | ||
|---|---|---|
Dioscoreae Rhizoma, also called Shan-Yao in Chinese, is a tonic food and herbal medicine in traditional Chinese medicine (TCM). Recent biomedical researches on Shan-Yao mainly focused on cancer and immune responses that are scattered in the literature. To build a holistic view of the immunoregulation functions delivered by Shan-Yao, the dispersed experimental knowledge items were collected, integrated, analyzed, and demonstrated. As a result, a candidate regulation network was constructed towards the immunoregulation. This network was composed of Shan-Yao, bioactive compounds, target proteins, protein interactions, pathway enrichment, and functional annotations. Functional annotations demonstrated the cell killing process is tightly associated with immunoregulation scenarios under different conditions via pathway enrichment, all are participated by the same target proteins of Shan-Yao. |
Year | DOI | Venue |
|---|---|---|
2020 | 10.1109/BIBM49941.2020.9313271 | BIBM |
DocType | Citations | PageRank |
Conference | 0 | 0.34 |
References | Authors | |
0 | 5 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Guang Zheng | 1 | 0 | 2.70 |
| Yarong Shi | 2 | 0 | 0.34 |
| Junnan Chen | 3 | 0 | 1.69 |
| Xiaohu Lu | 4 | 0 | 0.34 |
| Hongtao Guo | 5 | 29 | 9.71 |