Title | ||
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Potassium Monitoring From Multilead T-wave Morphology Changes During Hemodyalisis: Periodic Versus Principal Component Analysis |
Abstract | ||
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Background: End-stage renal disease (ESRD) patients undergoing hemodyalisis therapy (HD) experience blood potassium ([K+]) variations that are reflected on the T-wave (TW) morphology. Methods: We evaluated the performance of different lead space reduction (LSR) methods: principal component analysis (PCA), maximising the TW energy, and two derived versions of periodic component analysis (πCA) named πCA
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and πCA
<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub>
, maximising the QRST or TW beat periodicity. We applied these methods to 12-lead electrocardiogram (ECG) from 24 ESRD-HD patients. Then, we derived three markers of TW morphology changes (d
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, d
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and d
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), comparing an average TW derived every 30 min with that at the HD end, from the PCA, πCA
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and πCA
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based leads having the highest TW energy content. Similarities between these three methods were assessed by using Bland-Altman plots and the linear fitting error (ϵ) evaluated from the 12
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to the 44
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h of ECG recordings after the HD onset. Results: All series of d
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, d
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and d
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values showed good degree of mutual agreement (median bias ≤. 0.5 ms) and a small deviation from linearity in the [K+] increasing stage (median ϵ ≤ 3.3 ms). Conclusions: PCA and πCA can be used interchangeably to track TW changes in ESRD-HD patients, in this type of low noise contamination ECG recordings. |
Year | DOI | Venue |
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2020 | 10.22489/CinC.2020.199 | 2020 Computing in Cardiology |
Keywords | DocType | ISSN |
potassium monitoring,end-stage renal disease patients,principal component analysis,PCA,periodic component analysis,12-lead electrocardiogram,HD end,HD onset,multilead T-wave morphology,hemodyalisis therapy,blood potassium variations,lead space reduction methods,TW beat periodicity,QRST,ESRD-HD patients,TW energy content,Bland-Altman plots,linear fitting error,low noise contamination ECG recordings,time 30.0 min,K+ | Conference | 2325-8861 |
ISBN | Citations | PageRank |
978-1-7281-1105-6 | 0 | 0.34 |
References | Authors | |
0 | 9 |
Name | Order | Citations | PageRank |
---|---|---|---|
Flavio Palmieri | 1 | 0 | 0.34 |
Pedro Gomis | 2 | 0 | 0.34 |
José Esteban Ruiz | 3 | 0 | 0.34 |
Dina Ferreira | 4 | 0 | 0.34 |
Alba Martín-Yebra | 5 | 0 | 0.34 |
Esther Pueyo | 6 | 0 | 0.34 |
Pablo Laguna | 7 | 394 | 63.39 |
Juan Pablo Martínez | 8 | 0 | 0.34 |
Julia Ramírez | 9 | 0 | 1.01 |