Title
Quantitative Evaluation Of Burn Injuries Based On Electrical Impedance Spectroscopy Of Blood With A Seven-Parameter Equivalent Circuit
Abstract
A quantitative and rapid burn injury detection method has been proposed based on the electrical impedance spectroscopy (EIS) of blood with a seven-parameter equivalent circuit. The degree of burn injury is estimated from the electrical impedance characteristics of blood with different volume proportions of red blood cells (RBCs) and heated red blood cells (HRBCs). A quantitative relationship between the volume portion H-HCT of HRBCs and the electrical impedance characteristics of blood has been demonstrated. A seven -parameter equivalent circuit is employed to quantify the relationship from the perspective of electricity. Additionally, the traditional Hanai equation has been modified to verify the experimental results. Results show that the imaginary part of impedance Z(Imt) under the characteristic frequency (f(c)) has a linear relationship with H-HCT which could be described by Z(Imt) = -2.56H(HCT) - 2.01 with a correlation coefficient of 0.96. Moreover, the relationship between the plasma resistance R-p and H-HCT is obtained as R-p = -7.2H(HCT) + 3.91 with a correlation coefficient of 0.96 from the seven -parameter equivalent circuit. This study shows the feasibility of EIS in the quantitative detection of burn injury by the quantitative parameters Z(Imt) and R-p, which might be meaningful for the follow-up clinical treatment for burn injury.
Year
DOI
Venue
2021
10.3390/s21041496
SENSORS
Keywords
DocType
Volume
burn injury, electrical impedance spectroscopy, blood, red blood cell
Journal
21
Issue
ISSN
Citations 
4
1424-8220
0
PageRank 
References 
Authors
0.34
0
8
Name
Order
Citations
PageRank
Huilu Bao100.34
Jianping Li200.34
Jianming Wen300.34
Li Cheng400.34
Yili Hu500.34
Yu Zhang600.34
Nen Wan700.34
Masahiro Takei800.34