Title
Nano-Interstice Driven Powerless Blood Plasma Extraction In A Membrane Filter Integrated Microfluidic Device
Abstract
Blood plasma is a source of biomarkers in blood and a simple, fast, and easy extraction method is highly required for point-of-care testing (POCT) applications. This paper proposes a membrane filter integrated microfluidic device to extract blood plasma from whole blood, without any external instrumentation. A commercially available membrane filter was integrated with a newly designed dual-cover microfluidic device to avoid leakage of the extracted plasma and remaining blood cells. Nano-interstices installed on both sides of the microfluidic channels actively draw the extracted plasma from the membrane. The developed device successfully supplied 20 mu L of extracted plasma with a high extraction yield (similar to 45%) in 16 min.
Year
DOI
Venue
2021
10.3390/s21041366
SENSORS
Keywords
DocType
Volume
microfluidics, point-of-care testing, blood plasma extraction
Journal
21
Issue
ISSN
Citations 
4
1424-8220
0
PageRank 
References 
Authors
0.34
0
9
Name
Order
Citations
PageRank
Jaehoon Kim100.34
Junghyo Yoon200.34
Jae-Yeong Byun300.34
Hyunho Kim400.34
Sewoon Han500.34
Junghyun Kim600.34
Jeonghoon Lee7142.24
Han-Sang Jo800.34
Seok Chung900.68