Paper Info
Title
Predicting Recurrence for Patients With Ischemic Cerebrovascular Events Based on Process Discovery and Transfer Learning
Abstract
The recurrence of Ischemic cerebrovascular events (ICE) often results in a high rate of mortality and disability. However, due to the lack of labeled follow-up data in hospitals, prediction methods using traditional machine learning are usually not available or reliable. Therefore, we propose a new framework for predicting the long-term recurrence risk in patients with ICE after discharge from hospitals based on process mining and transfer learning, to point out high-risk patients for intervention. First, process models are discovered from clinical guidelines for analyzing the similarity of ICE population data collected by different medical institutions, and the control flow found are taken as added characteristics of patients. Then we use the in-hospital data (target domain) and the national stroke screening data (source domain), to develop risk prediction models applying instance filter and weight-based transfer learning method. To verify our method, 205 cases from a tertiary hospital and 2954 cases from the screening cohort (2015-2017) are tested. Experimental results show that our framework can improve the performance of three instance-based transfer algorithms. This study provides a comprehensive and efficient approach for applying transfer learning, to alleviate the limitation of insufficient labeled follow-up data in hospitals.
Year
DOI
Venue
2021
10.1109/JBHI.2021.3065427
IEEE Journal of Biomedical and Health Informatics
Keywords
DocType
Volume
Algorithms,Humans,Machine Learning,Stroke
Journal
25
Issue
ISSN
Citations 
7
2168-2194
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Haifeng Xu104.06
Jianfei Pang203.04
Weiliang Zhang300.34
Xuemeng Li402.37
Mei Li5211.53
Zhao Dongsheng606.42