Title
COBRAC: a fast implementation of convex biclustering with compression
Abstract
A Summary: Biclustering is a generalization of clustering used to identify simultaneous grouping patterns in observations (rows) and features (columns) of a data matrix. Recently, the biclustering task has been formulated as a convex optimization problem. While this convex recasting of the problem has attractive properties, existing algorithms do not scale well. To address this problem and make convex biclustering a practical tool for analyzing larger data, we propose an implementation of fast convex biclustering called COBRAC to reduce the computing time by iteratively compressing problem size along with the solution path. We apply COBRAC to several gene expression datasets to demonstrate its effectiveness and efficiency. Besides the standalone version for COBRAC, we also developed a related online web server for online calculation and visualization of the downloadable interactive results.
Year
DOI
Venue
2021
10.1093/bioinformatics/btab248
BIOINFORMATICS
DocType
Volume
Issue
Journal
37
20
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Haidong Yi133.17
Le Huang221.73
Gal Mishne301.01
Eric C. Chi411.03