Name
Title | ||
|---|---|---|
Droplet Transportation in MEDA-Based Biochips: An Enhanced Technique for Intelligent Cross-Contamination Avoidance |
Abstract | ||
|---|---|---|
Recent advances in microfluidics and microfabrication technology enabled the emergence of a new microelectrode-dot-array (MEDA) architecture for microfluidic biochips. The MEDA-based design allows dynamic routing with variable-sized droplets. The cross contamination avoidance between droplets of different biomolecules subjected for analysis and detection on MEDA architecture poses a major design challenge for development of MEDA-based biochips. In this article, we propose a precise technique for droplet routing with minimal cross contamination for MEDA-based biochips. Here we first evaluate the probability of cross contamination between any two droplets within the 2-D MEDA layout. Thereby, we propose a routing scheme for functional droplets specifically targeted for intelligent cross-contamination avoidance. As evident from the experimental results, the proposed technique effectively reduces both intra and inter subproblem cross contaminations. Experiment results shows considerable improvements over contemporary works. |
Year | DOI | Venue |
|---|---|---|
2021 | 10.1109/TVLSI.2021.3071410 | IEEE Transactions on Very Large Scale Integration (VLSI) Systems |
Keywords | DocType | Volume |
Algorithms,cross contamination,digital microfluidic biochip,droplet routing,microelectrode-dot-array (MEDA) architecture | Journal | 29 |
Issue | ISSN | Citations |
7 | 1063-8210 | 1 |
PageRank | References | Authors |
0.41 | 0 | 3 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Pampa Howladar | 1 | 1 | 1.09 |
| Pranab Roy | 2 | 47 | 14.15 |
| Hafizur Rahaman | 3 | 368 | 91.37 |