Title
Flip Learning: Erase to Segment
Abstract
Nodule segmentation from breast ultrasound images is challenging yet essential for the diagnosis. Weakly-supervised segmentation (WSS) can help reduce time-consuming and cumbersome manual annotation. Unlike existing weakly-supervised approaches, in this study, we propose a novel and general WSS framework called Flip Learning, which only needs the box annotation. Specifically, the target in the label box will be erased gradually to flip the classification tag, and the erased region will be considered as the segmentation result finally. Our contribution is three-fold. First, our proposed approach erases superpixel level using a Multi-agent Reinforcement Learning framework to exploit the prior boundary knowledge and accelerate the learning process. Second, we design two rewards: classification score and intensity distribution reward, to avoid under- and over-segmentation, respectively. Third, we adopt a coarse-to-fine learning strategy to reduce the residual errors and improve the segmentation performance. Extensively validated on a large dataset, our proposed approach achieves competitive performance and shows great potential to narrow the gap between fully-supervised and weakly-supervised learning.
Year
DOI
Venue
2021
10.1007/978-3-030-87193-2_47
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2021, PT I
Keywords
DocType
Volume
Ultrasound, Weakly-supervised segmentation, Reinforcement learning
Conference
12901
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
10
Name
Order
Citations
PageRank
Yuhao Huang103.72
Xin Yang2799.59
Yuxin Zou301.01
Chaoyu Chen402.03
Jian Wang531.76
Haoran Dou600.68
nishant ravikumar72312.43
Alejandro F. Frangi84333309.21
Jianqiao Zhou900.68
Dong Ni1036737.37