Paper Info
Title
Multi-Site Pulse Transit Times, Beat-to-Beat Blood Pressure, and Isovolumic Contraction Time at Rest and Under Stressors
Abstract
This study investigates the beat-to-beat relationships among Pulse Transit Times (PTTs) and Pulse Arrival Times (PATs) concomitantly measured from the heart to finger, ear and forehead vascular districts, and their links with continuous finger blood pressure and isovolumic contraction time (IVCT). These aspects were explored in 22 young volunteers at rest and during cold pressure test (CPT, thermal stress), handgrip (HG, isometric exercise) and cyclo-ergometer pedalling (CYC, dynamic exercise). The starting point of the PTT measures was detected by the seismocardiogram. Results indicate that PTTs measured at the ear, forehead and finger districts are uncorrelated each other at rest, and during CPT and HG. The stressors produced district-dependent changes in the PTT variability. Only the dynamic exercise was able to induce significant changes with respect to rest in the PTTs mean values (-40%, -36% and -17%, respectively for PTT <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ear</sub> , PTT <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">fore</sub> , PTT <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">finger</sub> ), and synchronize their modulations. Similar trends were observed in the PATs. IVCT decreased during the application of stressors with a minimum at CYC (-25%) reflecting an augmented heart contractility. The increase in blood pressure (BP) at CPT was greater than that at CYC (137 vs. 128 mmHg), but the correlations between beat-to-beat transit times and BP were maximal at CYC (PAT showed a higher correlation than PTT; correlations were greater for systolic than for diastolic BP). This suggests that pulse transit times do not always depend directly on the beat-to-beat BP values but, under specific conditions, on other factors and mechanisms that concomitantly also influence BP.
Year
DOI
Venue
2022
10.1109/JBHI.2021.3101976
IEEE Journal of Biomedical and Health Informatics
Keywords
DocType
Volume
Heart contractility,local hemodynamics,pulse arrival time,pulse wave velocity,seismocardi- ography,total peripheral resistance,vascular control
Journal
26
Issue
ISSN
Citations 
2
2168-2194
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Marco Di Rienzo18411.14
Albert Avolio23216.60
Giovannibattista Rizzo300.34
Zeynep Melike Isilay Zeybek400.34
Luisa Cucugliato500.34