Title
LipidQuant 1.0: automated data processing in lipid class separation-mass spectrometry quantitative workflows
Abstract
We present the LipidQuant 1.0 tool for automated data processing workflows in lipidomic quantitation based on lipid class separation coupled with high-resolution mass spectrometry. Lipid class separation workflows, such as hydrophilic interaction liquid chromatography or supercritical fluid chromatography, should be preferred in lipidomic quantitation due to the coionization of lipid class internal standards with analytes from the same class. The individual steps in the LipidQuant workflow are explained, including lipid identification, quantitation, isotopic correction and reporting results. We show the application of LipidQuant data processing to a small cohort of human serum samples.
Year
DOI
Venue
2021
10.1093/bioinformatics/btab644
BIOINFORMATICS
DocType
Volume
Issue
Conference
37
23
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
8