Title
Generator Versus Segmentor: Pseudo-healthy Synthesis
Abstract
This paper investigates the problem of pseudo-healthy synthesis that is defined as synthesizing a subject-specific pathology-free image from a pathological one. Recent approaches based on Generative Adversarial Network (GAN) have been developed for this task. However, these methods will inevitably fall into the trade-off between preserving the subject-specific identity and generating healthy-like appearances. To overcome this challenge, we propose a novel adversarial training regime, Generator versus Segmentor (GVS), to alleviate this trade-off by a divide-and-conquer strategy. We further consider the deteriorating generalization performance of the segmentor throughout the training and develop a pixel-wise weighted loss by muting the well-transformed pixels to promote it. Moreover, we propose a new metric to measure how healthy the synthetic images look. The qualitative and quantitative experiments on the public dataset BraTS demonstrate that the proposed method outperforms the existing methods. Besides, we also certify the effectiveness of our method on datasets LiTS. Our implementation and pre-trained networks are publicly available at https://github.corn/Au3C2/Generator-Versus-Segmentor.
Year
DOI
Venue
2021
10.1007/978-3-030-87231-1_15
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2021, PT VI
Keywords
DocType
Volume
Pseudo-healthy synthesis, Adversarial training, Medical images segmentation
Conference
12906
ISSN
Citations 
PageRank 
0302-9743
1
0.36
References 
Authors
0
9
Name
Order
Citations
PageRank
Yunlong Zhang111.37
Chenxin Li232.07
Xin Lin310.36
Liyan Sun4112.22
Yihong Zhuang511.03
Yue Huang631729.82
Xinghao Ding759152.95
Xiaoqing Liu812.05
Yizhou Yu92907181.26