Title
Self-adversarial Learning for Detection of Clustered Microcalcifications in Mammograms
Abstract
Microcalcification (MC) clusters in mammograms are one of the primary signs of breast cancer. In the literature, most MC detection methods follow a two-step paradigm: segmenting each MC and analyzing their spatial distributions to form MC clusters. However, segmentation of MCs cannot avoid low sensitivity or high false positive rate due to their variability in size (sometimes <0.1 mm), brightness, and shape (with diverse surroundings). In this paper, we propose a novel self-adversarial learning framework to differentiate and delineate the MC clusters in an end-to-end manner. The class activation mapping (CAM) mechanism is employed to directly generate the contours of MC clusters with the guidance of MC cluster classification and box annotations. We also propose the self-adversarial learning strategy to equip CAM with better detection capability of MC clusters by using the backbone network itself as a discriminator. Experimental results suggest that our method can achieve better performance for MC cluster detection with the contouring of MC clusters and classification of MC types.
Year
DOI
Venue
2021
10.1007/978-3-030-87234-2_8
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2021, PT VII
Keywords
DocType
Volume
Clustered microcalcifications, Class activation mapping, Self-adversarial learning
Conference
12907
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
9
Name
Order
Citations
PageRank
Xi Ouyang1274.86
Jifei Che200.34
Qitian Chen300.68
Zheren Li400.68
Yiqiang Zhan585958.54
Zhong Xue649645.70
Qian Wang753654.97
Jie-Zhi Cheng810213.00
Dinggang Shen97837611.27