Title
MSGSE-Net: Multi-scale guided squeeze-and-excitation network for subcortical brain structure segmentation
Abstract
Convolutional neural networks (CNNs) have been achieving remarkable results in medical image segmentation. However, for accurate segmentation of subcortical brain structure in MR images, it is still a challenge due to the ambiguous boundaries, the complex structures, and the various shapes, which limits their clinical application. In this paper, we focus on utilizing multi-scale image contexts and attention mechanisms to improve networks’ ability to learn discriminative feature representation for accurate segmentation and present a novel FCNN architecture called multis-scale guided squeeze-and-excitation network (MSGSE-Net). In particular, we first propose the multi-scale guided squeeze-and-excitation (MSGSE) attention module which can progressively and selectively aggregate discriminative features. In contrast to existing attention modules, the MSGSE module performs an adaptive recalibration that features at different locations of the feature map are recalibrated under the guidance of multi-scale contexts. Then multi-scale spatial attention supervision is adopted to enhance the intra-class homogeneity and inter-class distinction of the attention weights. Moreover, we propose a novel entropy-weighted Dice loss (EDL) to force the network to focus on the ambiguous voxels around the boundaries of subcortical structures. We evaluate the proposed method on two challenging benchmark datasets (the IBSR dataset and the MALC dataset). The experimental results show that our model consistently yields better segmentation performance than several state-of-the-art methods and improves the segmentation Dice score by 1.6% at most compared with baseline method U-Net. Our code is available at https://github.com/neulxlx/MSGSE-Net.
Year
DOI
Venue
2021
10.1016/j.neucom.2021.07.018
Neurocomputing
Keywords
DocType
Volume
Subcortical brain structure segmentation,Attention mechanism,Adaptive recalibration,Entropy-weighted Dice loss
Journal
461
ISSN
Citations 
PageRank 
0925-2312
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Xiang Li1566.55
Ying Wei2176.91
Lin Wang300.34
Shidi Fu400.34
Chuyuan Wang500.34