Paper Info
Title
Brain Networks Modulation in Young and Old Subjects During Transcranial Direct Current Stimulation Applied on Prefrontal and Parietal Cortex
Abstract
Evidence indicates that the transcranial direct current stimulation (tDCS) has the potential to transiently modulate cognitive function, including age-related changes in brain performance. Only a small number of studies have explored the interaction between the stimulation sites on the scalp, task performance, and brain network connectivity within the frame of physiological aging. We aimed to evaluate the spread of brain activation in both young and older adults in response to anodal tDCS applied to two different scalp stimulation sites: Prefrontal cortex (PFC) and posterior parietal cortex (PPC). EEG data were recorded during tDCS stimulation and evaluated using the Small World (SW) index as a graph theory metric. Before and after tDCS, participants performed a behavioral task; a performance accuracy index was computed and correlated with the SW index. Results showed that the SW index increased during tDCS of the PPC compared to the PFC at higher EEG frequencies only in young participants. tDCS at the PPC site did not exert significant effects on the performance, while tDCS at the PFC site appeared to influence task reaction times in the same direction in both young and older participants. In conclusion, studies using tDCS to modulate functional connectivity and influence behavior can help identify suitable protocols for the aging brain.
Year
DOI
Venue
2022
10.1142/S0129065721500568
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
Keywords
DocType
Volume
EEG, tDCS, task, network
Journal
32
Issue
ISSN
Citations 
01
0129-0657
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Miraglia, F132.48
Fabrizio Vecchio2134.06
Maria Concetta Pellicciari383.15
Jesus Cespon400.34
Paolo Maria Rossini56012.06