Paper Info
Title
A Flow Sensor-Based Suction-Index Control Strategy for Rotary Left Ventricular Assist Devices
Abstract
Rotary left ventricular assist devices (LVAD) have emerged as a long-term treatment option for patients with advanced heart failure. LVADs need to maintain sufficient physiological perfusion while avoiding left ventricular myocardial damage due to suction at the LVAD inlet. To achieve these objectives, a control algorithm that utilizes a calculated suction index from measured pump flow (SIMPF) is proposed. This algorithm maintained a reference, user-defined SIMPF value, and was evaluated using an in silico model of the human circulatory system coupled to an axial or mixed flow LVAD with 5-10% uniformly distributed measurement noise added to flow sensors. Efficacy of the SIMPF algorithm was compared to a constant pump speed control strategy currently used clinically, and control algorithms proposed in the literature including differential pump speed control, left ventricular end-diastolic pressure control, mean aortic pressure control, and differential pressure control during (1) rest and exercise states; (2) rapid, eight-fold augmentation of pulmonary vascular resistance for (1); and (3) rapid change in physiologic states between rest and exercise. Maintaining SIMPF simultaneously provided sufficient physiological perfusion and avoided ventricular suction. Performance of the SIMPF algorithm was superior to the compared control strategies for both types of LVAD, demonstrating pump independence of the SIMPF algorithm.
Year
DOI
Venue
2021
10.3390/s21206890
SENSORS
Keywords
DocType
Volume
left ventricular assist devices, sensor-based control, pump independent, suction index, physiological perfusion, suction prevention
Journal
21
Issue
ISSN
Citations 
20
1424-8220
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Lixue Liang100.34
Kai-Rong Qin204.06
Ayman El-Baz3661111.64
Thomas J Roussel400.34
Palaniappan Sethu593.39
guruprasad a giridharan667.47
Yu Wang7368.93