Title | ||
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Pre-implant Heart Activity Differs in Responders and Non-responders to Vagal Nerve Stimulation Therapy in Epileptic Patients |
Abstract | ||
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Vagal Nerve Stimulation (VNS) is used to treat patients with pharmacoresistant epilepsy. However, generally accepted tools to predict VNS response do not exist. Here we examined two heart activity measures - mean RR and pNN50 and their complex behavior during activation in pre-implant measurements. The ECG recordings of 73 patients (38 responders, 36 non-responders) were examined in a 30-sec floating window before (120 sec), during (2x120 sec), and after (120 sec) the hyperventilation by nose and mouth. The VNS response differentiation by pNN50 was significant (min p=0.01) in the hyperventilation by a nose with a noticeable descendant trend in nominal values. The mean RR was significant (p=0.01) in the rest after the hyperventilation by mouth but after an approximately 40-sec delay. |
Year | DOI | Venue |
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2021 | 10.1109/EMBC46164.2021.9629577 | 2021 43RD ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY (EMBC) |
DocType | Volume | ISSN |
Conference | 2021 | 1557-170X |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
10 |
Name | Order | Citations | PageRank |
---|---|---|---|
F Plesinger | 1 | 0 | 0.34 |
J Halamek | 2 | 0 | 0.34 |
J Chladek | 3 | 0 | 0.34 |
P Jurak | 4 | 0 | 0.34 |
A Ivora | 5 | 0 | 0.34 |
I Dolezalova | 6 | 0 | 0.34 |
E Koritakova | 7 | 0 | 0.34 |
T Jurkova | 8 | 0 | 0.34 |
J Chrastina | 9 | 0 | 0.34 |
M Brazdil | 10 | 0 | 0.34 |