Title
Prioritizing Disease Genes via Multi-View Nonnegative Matrix Factorization with Layer-Wise Explicit Hierarchical Constraint
Abstract
Prioritizing casual genes for disease phenotypes can reveal the inherent basis of human diseases and facilitate drug developments. It is widely believed that the full utilization of hierarchical structure of phenotype ontologies in HPO can improve the performance of gene prioritization significantly. However, previous works mostly utilize the hierarchical structure as graph constraint or implicit ...
Year
DOI
Venue
2021
10.1109/BIBM52615.2021.9669459
2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Keywords
DocType
ISBN
Drugs,Correlation,Conferences,Ontologies,Robustness,Bioinformatics,Diseases
Conference
978-1-6654-0126-5
Citations 
PageRank 
References 
0
0.34
0
Authors
7
Name
Order
Citations
PageRank
Xu Jin100.68
MingMing Liu211.36
WenQian He300.68
Lin Wang400.68
Ling Ma500.34
YaLou Huang600.34
Maoqiang Xie7367.62