Paper Info
Title
Predicting Spike Features of Hodgkin-Huxley-Type Neurons With Simple Artificial Neural Network
Abstract
Hodgkin-Huxley (HH)-type model is the most famous computational model for simulating neural activity. It shows the highest accuracy in capturing neuronal spikes, and its model parameters have definite physiological meanings. However, HH-type models are computationally expensive. To address this problem, a previous study proposed a spike prediction module (SPM) to predict whether a spike will take place 1 ms later based on three voltage values with intervals of 1 ms. Although SPM does well, it fails to evaluate the informative features of the spike. In this study, the feature prediction module (FPM) based on simple artificial neural network (ANN) was proposed to predict spike features including maximum voltage, minimum voltage, and dropping interval. Nine different HH-type models were adopted whose firing patterns cover most of the firing behaviors observed in the brain. Voltage and spike feature samples under constant external input current were collected for training and testing. Experiment results illustrated that the combination of SPM and FPM can accurately predict the spiking part of different HH-type models and can generalize to unseen types of input current. The combination of SPM and FPM may offer a possible way to simulate the action potentials of biological neurons with high accuracy and efficiency.
Year
DOI
Venue
2021
10.3389/fncom.2021.800875
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
Keywords
DocType
Volume
spike, Hodgkin-Huxley model, spike features prediction, artificial neural network, spike prediction module, feature prediction module
Journal
15
ISSN
Citations 
PageRank 
1662-5188
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Wang Tian11715.16
Ye Wang200.68
Jiamin Shen300.34
Lei Wang46554.21
Lihong Cao501.69