Name
Title | ||
|---|---|---|
On the Design of a PID Bio-Controller With Set Point Weighting and Filtered Derivative Action |
Abstract | ||
|---|---|---|
Effective and robust regulation of biomolecular processes is crucial for designing reliable synthetic bio-devices functioning in uncertain and constantly changing biological environments. Proportional-Integral-Derivative (PID) controllers are undeniably the most common way of implementing feedback control in modern technological applications. Here, we introduce a highly tunable PID bio-controller with set point weighting and filtered derivative action presented as a chemical reaction network with mass action kinetics. To demonstrate its effectiveness, we apply our PID scheme on a simple biological process of two mutually activated species, one of which is assumed to be the output of interest. To highlight its performance advantages we compare it to PI regulation using numerical simulations in both the deterministic and stochastic setting. |
Year | DOI | Venue |
|---|---|---|
2022 | 10.1109/LCSYS.2022.3182911 | IEEE CONTROL SYSTEMS LETTERS |
Keywords | DocType | Volume |
PD control, PI control, Steady-state, Biological system modeling, Biological processes, Topology, Stochastic processes, PID control, biomolecular systems, synthetic biology | Journal | 6 |
ISSN | Citations | PageRank |
2475-1456 | 0 | 0.34 |
References | Authors | |
0 | 3 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Emmanouil Alexis | 1 | 0 | 0.34 |
| Luca Cardelli | 2 | 6221 | 1002.41 |
| Antonis Papachristodoulou | 3 | 990 | 90.01 |