Title
Algorithmic Improvement and GPU Acceleration of the GenASM Algorithm
Abstract
We improve on GenASM, a recent algorithm for genomic sequence alignment, by significantly reducing its memory footprint and bandwidth requirement. Our algorithmic improvements reduce the memory footprint by 24 × and the number of memory accesses by 12 ×. We efficiently parallelize the algorithm for GPUs, achieving a 4.1 × speedup over a CPU implementation of the same algorithm, a 62× speedup over minimap2's CPU-based KSW2 and a 7.2 × speedup over the CPU-based Edlib for long reads.
Year
DOI
Venue
2022
10.1109/IPDPSW55747.2022.00038
2022 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW)
Keywords
DocType
ISSN
read mapping,sequence alignment,GPU,memory
Conference
2164-7062
ISBN
Citations 
PageRank 
978-1-6654-9748-0
1
0.34
References 
Authors
8
5
Name
Order
Citations
PageRank
Joël Lindegger110.68
Damla Senol Cali2343.32
Mohammed Alser3173.19
Juan Gómez-Luna4223.88
Onur Mutlu510.34