Name
Title | ||
|---|---|---|
The blood heat exchanger in intra-arterial selective cooling infusion for acute ischemic stroke: A computational fluid-thermodynamics performance, experimental assessment and evaluation on the brain temperature |
Abstract | ||
|---|---|---|
Intra-arterial selective cooling infusion with the autologous blood (IA-SCAI) is a promising therapeutic hypothermia induction method for conferring neuroprotection to acute ischemic stroke (AIS) patients. The blood heat exchanger (BHE) plays a crucial role in IA-SCAI's cooling capacity. However, there are no BHEs currently available that are specifically designed for the IA-SCAI, which requires a low blood flow to be compatible with cerebral hemodynamics. In an effort to develop a BHE for AIS patients, a prototype of a commercial BHE, Medtronic MYOtherm XP®, was mathematically modeled; specifically, computational fluid dynamics (CFD) was used to analyze its hemo- and thermo-dynamic characteristics under low blood flow including temperature distribution, velocity field and shear stress. |
Year | DOI | Venue |
|---|---|---|
2022 | 10.1016/j.compbiomed.2022.105497 | Computers in Biology and Medicine |
Keywords | DocType | Volume |
Blood heat exchanger,Therapeutic hypothermia,Stroke,Hemolysis,Numerical simulation | Journal | 145 |
ISSN | Citations | PageRank |
0010-4825 | 0 | 0.34 |
References | Authors | |
0 | 13 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Miaowen Jiang | 1 | 0 | 0.34 |
| Yuan Gao | 2 | 264 | 47.87 |
| Chuanjie Wu | 3 | 0 | 0.34 |
| Longfei Wu | 4 | 0 | 0.34 |
| Shoucheng Tang | 5 | 0 | 0.34 |
| Zhichen Yin | 6 | 0 | 0.34 |
| Ang Li | 7 | 0 | 0.34 |
| Kun Wang | 8 | 0 | 0.34 |
| Shiqiang Zheng | 9 | 43 | 12.97 |
| Hangil Lee | 10 | 0 | 0.34 |
| Yuchuan Ding | 11 | 0 | 0.34 |
| Ming Li | 12 | 15 | 9.78 |
| Xunming Ji | 13 | 0 | 1.01 |