Title
Differentiable Zooming for Multiple Instance Learning on Whole-Slide Images.
Abstract
Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue patches. Such a formulation induces high computational requirements, and constrains the contextualization of the WSI-level representation to a single scale. A few MIL methods extend to multiple scales, but are computationally more demanding. In this paper, inspired by the pathological diagnostic process, we propose ZoomMIL, a method that learns to perform multi-level zooming in an end-to-end manner. ZoomMIL builds WSI representations by aggregating tissue-context information from multiple magnifications. The proposed method outperforms the state-of-the-art MIL methods in WSI classification on two large datasets, while significantly reducing the computational demands with regard to Floating-Point Operations (FLOPs) and processing time by up to 40x.
Year
DOI
Venue
2022
10.1007/978-3-031-19803-8_41
European Conference on Computer Vision
DocType
Citations 
PageRank 
Conference
0
0.34
References 
Authors
0
7
Name
Order
Citations
PageRank
Kevin Thandiackal100.34
Boqi Chen200.34
Pushpak Pati300.34
Guillaume Jaume412.75
Drew F. K. Williamson500.34
Maria Gabrani6307.27
Orçun Göksel7318.92