Title
Research on data classification and feature fusion method of cancer nuclei image based on deep learning
Abstract
There are many different types of nuclei in a tumor tissue. We can identify the specific nuclei and their distribution in the tissue to reflect the current cancer state of histopathological images. However, due to the existence of cellular heterogeneity, the recognition of nuclei in histopathological images has always been a problem of computer vision. In the paper, we use the transfer learning of Deep Convolutional Neural Network to classify nuclei, and found that adjusting the size of the nuclear image to a certain size can improve the accuracy of the nuclei classification model, while not significantly reducing the nuclei classification efficiency. Through further research, it was confirmed that the environment around the nuclei can bring great help to the model classification. Based on the principle, we design a feature fusion model. We extract features from nuclei image different sizes by CNN, fuse the features, and then use fully connected layer to classify the features. Experiments have proved that the feature fusion model has a considerable improvement in accuracy compared to the normal classification model.
Year
DOI
Venue
2022
10.1002/ima.22676
INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY
Keywords
DocType
Volume
cancer cell image, classification, deep learning, feature fusion model, multiscale image
Journal
32
Issue
ISSN
Citations 
3
0899-9457
0
PageRank 
References 
Authors
0.34
0
8
Name
Order
Citations
PageRank
Shanshan Liu100.68
Ruo Hu200.34
Jianfang Wu300.34
Xizheng Zhang400.68
Jun He501.01
Huimin Zhao611.03
Huajia Wang701.35
Xiangjun Li882.46