Title
High-Frequency rTMS Combined with Task-Specific Hand Motor Training Modulates Corticospinal Plasticity in Motor Complete Spinal Cord Injury: A case report.
Abstract
Since its first use in spinal cord injury (SCI) in the early 2000s [1], high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) demonstrated a capacity to modulate corticospinal excitability (CSE) and motor performance. Studies focused on individuals with incomplete SCI. Here, we examined the feasibility of a 15-day therapeutic stimulation protocol combining HF-rTMS with task-specific motor training targeting the weaker hand in an individual with early chronic complete SCI. In this case report, we present evidence of progressive increase of CSE at rest and during muscle activation, and decreased cortical inhibition, associated with a trend toward improvement in pinch function of the weaker hand. These promising findings need to be confirmed in a larger population. Clinical Relevance- These preliminary results are promising and demonstrate the importance of a large number of training session repetitions to induce consistent changes relevant to the recovery after a complete SCI.
Year
DOI
Venue
2022
10.1109/EMBC48229.2022.9871134
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
DocType
Volume
ISSN
Conference
2022
2694-0604
Citations 
PageRank 
References 
0
0.34
0
Authors
8
Name
Order
Citations
PageRank
Nabila Brihmat100.34
Mehmed Bugrahan Bayram200.68
Didier Allexandre301.01
Soha Saleh401.01
Guang H Yue500.34
Xiaofei Guan600.68
Jian Zhong752.85
Gail F Forrest800.68